Of course, any change to that historic moment could potentially change the entirety of Star Trek as a whole. The destruction of Romulus resulted in Nero’s arrival back in time via a time vortex, which created the Kelvin timeline. Unless the goal of Star Trek: Picard Season 2 is to retcon the J.J. Abrams films, I can’t imagine there’d be any lasting change that prevented Nero’s actions. Perhaps Q has plans to send Picard elsewhere, or we’ll ultimately learn that, regardless of what Starfleet did that day, the result was the same. All we know is that Q will return, which usually means some craziness for Picard and others.